Chefarzt Priv. Doz. Dr. med. Jon Jones

Originalarbeiten

Pathway analysis of high-throughput biological data within a Bayesian network framework.Isci S, Ozturk C, Jones J, Otu HH. Bioinformatics. 2011 Jun 15;27(12):1667-74. Epub 2011 May 5.

Intraoperative peripheral frozen sections do not significantly affect prognosis after nerve-sparing radical prostatectomy for prostate cancer. Gillitzer R, Thüroff C, Fandel T, Thomas C, Thüroff JW, Brenner W, Wiesner C, Jones J, Hansen T, Hampel C. BJU Int. 2011 Mar;107(5):755-9.

Alterations of the gene expression profile in renal cell carcinoma after treatment with the histone deacetylase-inhibitor valproic acid and interferon-alpha. Juengel E, Bhasin M, Libermann T, Barth S, Michaelis M, Cinatl J Jr, Jones J, Hudak L, Jonas D, Blaheta RA. World J Urol. 2010 Jul 17. [Epub ahead of print]

Association of intravesical tumor location with metastases to the pelvic lymph nodes in transitional cell cancer of the bladder. Wedel SA, Jones J, Tsaur I, Ackermann H, Beecken WD, Jonas D, Blaheta R. Am J Med Sci. 2010 Apr;339(4):341-4.

Single Center Comparison of Anastomotic Strictures After Radical Perineal and Radical Retropubic Prostatectomy. Gillitzer R, Thomas C, Wiesner C, Jones J, Schmidt F, Hampel C, Brenner W, Thüroff JW, Melchior SW. Urology. 2010 Aug;76(2):417-422.

Incidence, clinical symptoms and management of rectourethral fistulas after radical prostatectomy. Thomas C, Jones J, Jäger W, Hampel C, Thüroff JW, Gillitzer R. J Urol. 2010 Feb;183(2):608-12..

Melchior S, Cudovic D, Jones J, Thomas C, Gillitzer R, Thüroff J.
Diagnosis and surgical management of colovesical fistulas due to sigmoid diverticulitis. J Urol. 2009 Sep;182(3):978-82. 

Juengel E, Engler J, Mickuckyte A, Jones J, Hudak L, Jonas D, Blaheta RA.
Effects of combined valproic acid and the epidermal growth factor/vascular endothelial growth factor receptor tyrosine kinase inhibitor AEE788 on renal cell carcinoma cell lines in vitro. BJU Int. 2010 Feb;105(4):549-57.

Tsaur I, Jones J, Melamed RJ, Blaheta RA, Gossmann J, Bentas W. Postoperative voiding dysfunction in older male renal transplant recipients. Transplant Proc. 2009 Jun;41(5):1615-8.

Juengel E, Engler J, Natsheh I, Jones J, Mickuckyte A, Hudak L, Jonas D, Blaheta RA. Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells. BMC Cancer. 2009 May 27;9:161. 

Jones J, Juengel E, Mickuckyte A, Hudak L, Wedel S,  Jonas D, Blaheta RA. The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo. J Cell Mol Med. 2008 Jul 24. [Epub ahead of print] 

Jones J, Bentas W, Blaheta RA, Makarević J, Hudak L, Wedel S, Probst M, Jonas D, Juengel E. Modulation of adhesion and growth of colon and pancreatic cancer cells by the histone deacetylase inhibitor valproic acid. Int J Mol Med. 2008 Sep;22(3):293-9.

Bentas W, Jones J*, Urbschat A, Tilp U, Probst M, Scheuermann E, Hauser IA, Blaheta RA, Jonas D, Gossmann J. Effect of procurement-related organ lesions on renal transplant outcome. Clin Transplant. 2008 Feb 2; (*WB and JJ contributed equally)

Bentas W, Jones J, Karaoguz A, Tilp U, Probst M, Scheuermann E, Hauser IA, Jonas D, Gossmann J. Renal transplantation in the elderly: surgical complications and outcome with special emphasis on the Eurotransplant Senior Programme. Nephrol Dial Transplant. 2008 Jan 18

Jones J, Otu HH, Grall F, Spentzos D, Can H, Aivado M, Belldegrun AS, Pantuck AJ, Libermann TA. Proteomic identification of interleukin-2 therapy response in metastatic renal cell cancer. J Urol. 2008 Feb;179(2):730-6. 

Jones J, Berkhoff S, Weich E, Engl T, Wedel S, Relja B, Jonas D, Blaheta RA. Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes. J Cell Mol Med. 2007 Jul-Aug;11(4):826-38.

Jones J, Marian D, Weich E, Engl T, Wedel S, Relja B, Jonas D, Blaheta RA. CXCR4 chemokine receptor engagement modifies integrin dependent adhesion of renal carcinoma cells. Exp Cell Res. 2007 Nov 15;313(19):4051-65.

Jones J, Otu H, Spentzos D, Kolia S, Inan M, Beecken WD, Fellbaum C, Gu X, Joseph M, Pantuck AJ, Jonas D, Libermann TA. Gene signatures of progression and metastasis in renal cell cancer. Clin Cancer Res. 2005 Aug 15;11(16):5730-9.

Oertl AJ, Jonas D, Oremek GM, Jones J*. Saphenous vein interposition as a salvage technique for complex vascular situations during renal transplantation.
Transplant Proc. 2007 Jan-Feb;39(1):140-2. (*AO and JJ contributed equally)

Bentas W, Probst M, Jones J, Karaoguz A, Cerovac I, Scheuermann E, Hauser IA, Jonas D, Gossmann J. [Quality of kidney procurement in Germany. Ten years experience and 486 renal allografts in a single centre] Urologe A. 2007 Mar;46(3):268-70, 271-3. German.

Blaheta RA, Weich E, Marian D, Bereiter-Hahn J, Jones J, Jonas D, Michaelis M, Doerr HW, Cinatl J Jr. Human cytomegalovirus infection alters PC3 prostate carcinoma cell adhesion to endothelial cells and extracellular matrix. Neoplasia. 2006 Oct;8(10):807-16.

Oertl A, Relja B, Makarevic J, Weich E, Höfler S, Jones J, Jonas D, Bratzke H, Baer PC, Blaheta RA. Altered expression of beta1 integrins in renal carcinoma cell lines exposed to the differentiation inducer valproic acid. Int J Mol Med. 2006 Aug;18(2):347-54.

Wedel SA, Mickuckyte A, Juengel E, Jones J, Hudak L, Jonas D, Blaheta RA. Preclinical studies on the influence of the tyrosine kinase inhibitor AEE788 on malignant properties of renal cell carcinoma cells. Urologe A. 2008 Aug 9. [Epub ahead of print]

Engl T, Relja B, Marian D, Blumenberg C, Müller I, Beecken WD, Jones J, Ringel EM, Bereiter-Hahn J, Jonas D, Blaheta RA. CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins. Neoplasia. 2006 Apr;8(4):290-301.

Bentas W, Wolfram M, Jones J, Bräutigam R, Kramer W, Binder J. Robotic technology and the translation of open radical prostatectomy to laparoscopy: the early Frankfurt experience with robotic radical prostatectomy and one year follow-up. Eur Urol. 2003 Aug;44(2):175-81.

Binder J, Jones J, Bentas W, Wolfram M, Bräutigam R, Probst M, Kramer W, Jonas D. [Robot-assisted laparoscopy in urology. Radical prostatectomy and reconstructive retroperitoneal interventions] Urologe A. 2002 Mar;41(2):144-9. German.

Review Artikel

Jones J , Thüroff JW. Clinical Trials Report: Pazopanib for Advanced Renal Cell Carcinoma: Comments on the Results From the Phase 3 Study. Current Urology Reports. 2010 Nov;11(6):364-5.

Jones J, Hampel Ch. Erweiterung des Donorpools in der Nierentransplantation. Urologe A. 2009 Dec;48(12):1459-63

Jones J and Pantuck AJ Genomics and Proteomics in Renal Cell Carcinoma: Diagnosis, Prognosis, and Treatment Selection
Current Urology Reports 2008 Jan; Volume 9, Issue 1; pp.9-14

Jones J and Libermann TA. Genomics of renal cell cancer: the biology behind and the therapy ahead. Clin Cancer Res. 2007 Jan 15;13(2 Pt 2):685s-692s. Review.

Buchartikel

Jones J, Beecken WD, Kramer W. Erkrankungen der Niere und der ableitenden Harnwege. In: Nierenerkrankungen. Pathophysiologie, Diagnostik und Therapie. Kap. 12; 439-456. Geiger, Jonas, Lenz, Kramer.  Schattauer Verlag.

Beecken WD, Jones J, Kramer W. Nierenverletzungen. In: Nierenerkrankungen. Pathophysiologie, Diagnostik und Therapie.  Kap. 12; 425-437. Geiger, Jonas, Lenz, Kramer.  Schattauer Verlag.

Case reports

Jones J, Melchior SW, Gillitzer R, Fichtner J, El-Mekresh M, Thüroff JW. Urethral recurrence of transitional cell carcinoma in a female patient after cystectomy and orthotopic ileal neobladder. J Urol. 2000 Nov;164(5):1646.

Jones J, Bickeböller R, Binder J, Kramer W. Synchronous bladder augmentation and living related kidney transplantation.  Urol. Int.  2001; 67(1):84-5.

Jones J, Dahms SE, Fichtner J, Hohenfellner M, Thüroff JW. An unusual case of ureteral ectopia in the seminal vesicle: diagnosis and surgical management. Urol Int. 1999;62(2):130-2.

Gillitzer R, Melchior SW, Jones J, Fichtner J, Thüroff JW. Prostatosymphyseal fistula after transurethral resection of the prostate. J Urol. 2001 Sep;166(3):1001-2.

Dahms SE, Jones J, Hampel C., Fichtner J., Hohenfellner M., Hohenfellner R., Thüroff JW. Zystische Samenblasenveränderungen: Eine retrospektive Analyse. Aktuelle Urologie 1999; 30: 52-58.

Preise

2008 Clinical Science Award, Deutsche Gesellschaft für Immuntherapie

2004 Experimental Poster Prize, Deutsche Gesellschaft für Urologie (DGU)

2003 Erster Poster Preis, Combined Prostate and Kidney Cancer SPORE retreat, Dana Farber/Harvard Cancer Center

2003 Innovationspreis, Deutsche Gesellschaft für Urologie (DGU)

2003 und 2004 Developmental Project Award, DF/Harvard Cancer Center Renal Cancer, SPORE (specialized project of research excellence)

Mitgliedschaften

Deutsche Gesellschaft für Urologie (DGU)

European Association of Urology (EAU)

Interdisziplinäre Arbeitsgruppe Nierentumore (IAG-N)

American Association of Urology (AUA)